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Diffusion of Contrast Agents in Cartilage Under Static Compression
Full Title
Diffusion of MRI and CT contrast agents in articular cartilage under static compression
Summary
This study investigated the effects of static compression on nutrient transport in articular cartilage using MRI and CT contrast agents. The results showed that compression significantly reduced the diffusion of both small and large solutes into cartilage. The findings support the conclusion that sustained mechanical pressure can impair nutrient access and overall cartilage health, providing a mechanistic basis for how static loading may contribute to tissue dysfunction or injury.