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Biological Responses of Tissues to Stressors
Full Title
Biological Responses of Tissues to Stressors
Summary
This extensive review outlines how repeated mechanical stress and reinjury can disrupt the healing process in ligaments and tendons. It describes that when tendons or related soft tissues are exposed to repetitive strain before sufficient healing has occurred, they undergo degenerative changes. These include inflammation, disorganized collagen fiber structure, vascular proliferation, and interstitial edema. The cumulative effect of this repeated microtrauma can lead to scar formation and chronic dysfunction, making full recovery more difficult. The study highlights that avoiding premature reloading of healing tissues is critical to prevent long-term damage and delayed or incomplete recovery.