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Platelet-Rich Plasma Injection for Acute Achilles Tendon Rupture (PATH-2 Trial)
Full Title
Platelet-rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo-controlled, superiority trial
Summary
This multicenter, double-blind randomized controlled trial assessed the efficacy of PRP injections in 230 adults with acute Achilles tendon ruptures. Participants received either a PRP injection or a placebo (dry needle) alongside standard rehabilitation. At 24 weeks, there were no significant differences between the groups in muscle-tendon function, patient-reported outcomes, or quality of life. The study concluded that PRP injections did not provide additional benefits over placebo in the recovery from acute Achilles tendon ruptures.